Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483014 | 0.85 | NQO1 (0.48) | TP53ALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11469809 | 0.81 | CNR1 (0.47) | TP53ALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11273639 | 0.81 | GPR84 (0.49) | TP53ALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL11470726 | 0.80 | TP53 (0.50) | TP53ALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11469872 | 0.80 | CACNA2D1 (0.48) | TP53ALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11467932 | 0.78 | TP53 (0.45) | TP53ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL11485851 | 0.78 | TP53 (0.54) | TP53ALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL11483854 | 0.78 | MAPT (0.42) | TP53ALDH1A1HTTNPSR1LMNA | |
| SCHEMBL11469963 | 0.77 | GAA (0.48) | TP53ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL11239685 | 0.77 | PTGES (0.50) | ALDH1A1HTTNPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |