Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluquazone SCHEMBL43464 | 0.90 | MAPT (0.58) | RXFP1MAPTTP53LMNAKCNH2 | |
| SCHEMBL11479043 | 0.85 | NR1I2 (0.59) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11162361 | 0.84 | LMNA (0.54) | RXFP1MAPTTP53LMNA | |
| Fluquazone SCHEMBL28193448 | 0.84 | MAPT (0.57) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11468901 | 0.82 | CASR (0.51) | MAPTTP53LMNANR1I2ADORA3 | |
| SCHEMBL11480424 | 0.82 | MAPT (0.57) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11470963 | 0.82 | MAPT (0.57) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11468011 | 0.81 | MAPT (0.56) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11632380 | 0.80 | RXFP1 (0.48) | RXFP1MAPTTP53LMNAKDM4E | |
| SCHEMBL11460777 | 0.80 | MAPT (0.42) | RXFP1MAPTTP53LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |