Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160129 | 0.90 | NR1I2 (0.50) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11479018 | 0.85 | RXFP1 (0.51) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11468014 | 0.85 | LMNA (0.56) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11468901 | 0.85 | CASR (0.51) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11162361 | 0.84 | LMNA (0.54) | LMNAMAPTTP53RXFP1POLB | |
| SCHEMBL11858866 | 0.81 | ALDH1A1 (0.39) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11459543 | 0.81 | PDE3B (0.47) | LMNAMAPTTP53KDM4EALDH1A1 | |
| SCHEMBL11462815 | 0.81 | NR1I2 (0.48) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11165951 | 0.80 | NR1I2 (0.58) | NR1I2EGFRADRA2AADORA3TBXA2R | |
| SCHEMBL11462895 | 0.79 | MAPT (0.44) | LMNAMAPTPTGER1TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |