Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015657 | 0.74 | BRD4 (0.43) | MAPTALDH1A1 | |
| SCHEMBL31058537 | 0.71 | ALDH1A1 (0.40) | MAPTALDH1A1ACHEKDM4EKMT2A | |
| SCHEMBL27891264 | 0.70 | MAPT (0.49) | MAPTALDH1A1ACHEKDM4EMEN1 | |
| SCHEMBL2316644 | 0.69 | MAPT (0.44) | MAPTALDH1A1ACHEKDM4EMEN1 | |
| SCHEMBL17192666 | 0.66 | HTR6 (0.44) | MAPTALDH1A1HTR6CYP2C9HTR2A | |
| SCHEMBL777971 | 0.66 | MAPT (0.56) | MAPTALDH1A1ACHEKDM4EMEN1 | |
| SCHEMBL7541817 | 0.66 | HTR2A (0.56) | MAPTALDH1A1ACHEKDM4EMEN1 | |
| SCHEMBL3392609 | 0.66 | MAPT (0.55) | MAPTALDH1A1ACHEKDM4EMEN1 | |
| SCHEMBL2048495 | 0.65 | HTR2A (0.59) | MAPTALDH1A1HTR6HTR2AHTR2C | |
| SCHEMBL776895 | 0.65 | MAPT (0.55) | MAPTALDH1A1ACHEKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206140-A | INSECTICIDES, ANTHELMINTICS | ROUSSEL UCLAF (FR) | 1980-06-03 | — | — | US | disclosed |
| US-4101574-A | Cyclopropanecarboxylic acid chlorides | ROUSSEL UCLAF (FR) | 1978-07-18 | — | — | US | disclosed |
| US-3997586-A | Cyclopropanecarboxylic acids and esters | ROUSSEL-UCLAF (FR) | 1976-12-14 | — | — | US | disclosed |