Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478104 | 0.88 | AKR1C3 (0.39) | KMT2AMAPTPOLB | |
| SCHEMBL28381581 | 0.88 | AKR1C3 (0.41) | KMT2AMAPTLMNAMAPK1POLB | |
| SCHEMBL10948913 | 0.88 | ALDH1A1 (0.35) | KMT2AMAPTBDKRB1 | |
| SCHEMBL9748582 | 0.83 | NR4A1 (0.44) | NR4A1KMT2AMAPTBRD4LMNA | |
| SCHEMBL9747885 | 0.80 | PGR (0.43) | NR4A1KMT2AMAPTBRD4LMNA | |
| SCHEMBL10952280 | 0.79 | ALDH1A1 (0.37) | MAPTBDKRB1 | |
| SCHEMBL10949243 | 0.77 | KMT2A (0.37) | KMT2AMAPTLMNA | |
| SCHEMBL117727 | 0.75 | CACNB4 (0.40) | MAPT | |
| SCHEMBL10950018 | 0.74 | MEN1 (0.39) | KMT2AMAPTLMNA | |
| SCHEMBL10951474 | 0.72 | ALDH1A1 (0.34) | KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975531-A | ANTIINFLAMMATORY | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-08-17 | — | — | US | claimed |
| US-4182774-A | Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof | A. H. ROBINS COMPANY, INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |
| US-4126635-A | ANTICHOLESTEROL, BLOOD PLATELET AGGREGATION INHIBITION | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-11-21 | — | — | US | disclosed |
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | disclosed |
| US-3975531-A | ANTIINFLAMMATORY | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-08-17 | — | — | US | disclosed |