Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11470521 | 0.90 | GPR84 (0.53) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL11477811 | 0.85 | GPR84 (0.53) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL11231246 | 0.80 | GPR84 (0.54) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL11469393 | 0.78 | TP53 (0.46) | GPR84ALDH1A1LMNANPSR1KDM4E | |
| SCHEMBL11468338 | 0.77 | PTGES (0.53) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9695587 | 0.77 | GPR84 (0.52) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL11476538 | 0.76 | TP53 (0.62) | ALDH1A1LMNANPSR1L3MBTL1KDM4E | |
| SCHEMBL9696190 | 0.76 | GPR84 (0.51) | GPR84ALDH1A1LMNANPSR1L3MBTL1 | |
| SCHEMBL10509045 | 0.75 | NPSR1 (0.53) | ALDH1A1LMNANPSR1L3MBTL1KDM4E | |
| SCHEMBL11711874 | 0.75 | GPR84 (0.51) | GPR84ALDH1A1LMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |