SCHEMBL1147321

SCHEMBL1147321

O=C(CCCCC(=O)OCCC(Cl)Cl)OCCC(Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.48
DNM1 Q05193 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
MAPT P10636 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA1A P35348 1/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BLM P54132 1/20 0.35
PAM P19021 2/20 0.35
KDM4E B2RXH2 1/20 0.35
DUSP3 P51452 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557674 0.83 LMNA (0.39) DGKACYP3A4TDP1MAPTADRA2A
SCHEMBL27842613 0.79 DGKA (0.52) DGKADNM1CYP3A4TSHRATM
SCHEMBL15422454 0.79 CYP19A1 (0.30)
SCHEMBL27860104 0.78 DGKA (0.55) DGKADNM1CYP3A4TSHRATM
SCHEMBL249563 0.77 DGKA (0.54) DGKADNM1CYP3A4TSHRATM
SCHEMBL4540053 0.77 DGKA (0.48) DGKADNM1CYP3A4TSHRATM
SCHEMBL247200 0.76 DGKA (0.57) DGKADNM1CYP3A4TSHRATM
SCHEMBL494939 0.76 DGKA (0.57) DGKADNM1CYP3A4TSHRATM
SCHEMBL494198 0.76 DGKA (0.57) DGKADNM1CYP3A4TSHRATM
SCHEMBL494383 0.76 DGKA (0.57) DGKADNM1CYP3A4TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053034-B1 Process for producing a chlorohydrin SOLVAY (BE) 2018-01-24 EP disclosed
US-9663427-B2 Process for producing epichlorohydrin Solvay (Société Anonyme) (BE) 2017-05-30 US disclosed
EP-1775278-B1 Process for producing epoxy resins SOLVAY (BE) 2016-04-13 EP disclosed
EP-1760060-B1 Process for producing dichloropropanol from glycerol SOLVAY (BE) 2015-01-14 EP disclosed
US-8415509-B2 Process for producing dichloropropanol from glycerol, the glycerol coming eventually from the conversion of animal fats in the manufacture of biodiesel SOLVAY (SOCIETE ANONYME) (BE) 2013-04-09 US disclosed
EP-1752435-B1 Process for producing epichlorhydrin SOLVAY (BE) 2012-06-06 EP disclosed
EP-1687248-B1 PROCESS FOR PRODUCING DICHLOROPROPANOL FROM GLYCEROL AND A CHLORINATED AGENT AND IN THE PRESENCE OF A CATALYST SELECTED FROM ADIPIC AND GLUTARIC ACID SOLVAY (BE) 2011-06-01 EP disclosed
EP-2053035-B1 Process for producing dichloropropanol SOLVAY (BE) 2011-03-16 EP disclosed
US-7893193-B2 Involves reacting renewable polyhydroxyl compound such as glycerol and/or an ester thereof, with a chlorinating agent and an organic acid to give a mixture containing the chlorohydrin and esters of the chlorohydrin Solvay (Société Anonyme) (BE) 2011-02-22 US disclosed
EP-2284147-A2 Process for producing dichloropropanol SOLVAY (Société Anonyme) (BE) 2011-02-16 EP disclosed
US-20090131631-A1 METHOD FOR MAKING A CHLOROHYDRIN SOLVAY (SOCIETE ANONYME) (BE) 2009-05-21 US disclosed
EP-2053034-A1 Process for producing a chlorohydrin SOLVAY (Société Anonyme) (BE) 2009-04-29 EP disclosed
EP-2053035-A1 Process for producing dichloropropanol SOLVAY (Société Anonyme) (BE) 2009-04-29 EP disclosed
US-20070112224-A1 Process for producing dichloropropanol from glycerol, the glycerol coming eventually from the conversion of animal fats in the manufacture of biodiesel SOLVAY (SOCIETE ANONYME) (BE) 2007-05-17 US disclosed
EP-1775278-A1 Process for producing epoxy resins SOLVAY (Société Anonyme) (BE) 2007-04-18 EP disclosed
EP-1772446-A1 Process for producing organic compounds from glycerol , the glycerol coming from renewable raw material SOLVAY (Société Anonyme) (BE) 2007-04-11 EP disclosed
EP-1770081-A1 Process for producing dichloropropanol from glycerol , the glycerol coming eventualy from the conversion of animal fats in the manufacture of biodiesel SOLVAY (Société Anonyme) (BE) 2007-04-04 EP disclosed
EP-1760060-A1 Process for producing dichloropropanol from glycerol SOLVAY (Société Anonyme) (BE) 2007-03-07 EP disclosed
EP-1752435-A1 Process for producing dichloropropanol from glycerol , the glycerol coming eventualy from the manufacture of biodiesel SOLVAY (Société Anonyme) (BE) 2007-02-14 EP disclosed
EP-1752436-A1 Pseudo-azeotropic composition containing dichloropropanol and process for producing such composition SOLVAY (Société Anonyme) (BE) 2007-02-14 EP disclosed