Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147321 | 0.83 | DGKA (0.48) | LMNAADRA2AADRA1AMAPTBLM | |
| SCHEMBL28687972 | 0.81 | LMNA (0.40) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| SCHEMBL409092 | 0.79 | LMNA (0.53) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| SCHEMBL13575623 | 0.79 | CYP19A1 (0.45) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| SCHEMBL27290491 | 0.78 | LMNA (0.41) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| SCHEMBL11077835 | 0.78 | ADRA2A (0.47) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| SCHEMBL30207417 | 0.77 | LMNA (0.50) | LMNAADRA2AADRA1AKDM2AEGLN1 | |
| Succinic Acid SCHEMBL30975323 | 0.76 | GRM8 (0.57) | BLMFOLH1CYP1A2GRM8GRM6 | |
| SCHEMBL2263150 | 0.76 | GRM8 (0.57) | BLMFOLH1CYP1A2GRM8GRM6 | |
| SCHEMBL2263158 | 0.76 | GRM8 (0.57) | BLMFOLH1CYP1A2GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110327439-A | Traditional Chinese drug mixture and preparation method thereof containing Japanese Flowering Fern Rhizome and fructus amomi | 数源汇通（北京）医药科技有限公司 | 2019-10-15 | — | — | CN | disclosed |
| CN-107753598-A | A kind of composition for treating chronic rhinitis | 山西东方亮生命科技股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-1190197-C | Application of cyanoquinoline in preparing medicine for treating or inhibiting colonic polyp | HEWLETT HOLDINGS CORP (US) | 2005-02-23 | — | — | CN | disclosed |
| EP-0826671-B1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| CN-1429126-A | Use of cyanoquinolines for treating or inhibiting colonic polyps | AMERICAN CYANAMID CO (US) | 2003-07-09 | — | — | CN | disclosed |
| US-5948785-A | USEFUL AS CHYMASE INHIBITORS AND CAN BE EFFECTIVE FOR THE PROPHYLAXIS AND TREATMENT OF VARIOUS DISEASES CAUSED BY CHYMASE, SUCH AS THOSE CAUSED BY ANGIOTENSIN II. | THE GREEN CROSS CORPORATION (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0826671-A1 | HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME | THE GREEN CROSS CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |