Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464894 | 0.83 | PLK1 (0.66) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| SCHEMBL7218991 | 0.78 | NR4A1 (0.71) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| SCHEMBL29494693 | 0.78 | NR4A1 (0.71) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| SCHEMBL9826699 | 0.77 | LMNA (0.48) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL11583883 | 0.77 | ALDH1A1 (0.56) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| SCHEMBL28590614 | 0.76 | CES2 (0.59) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11471653 | 0.75 | SMN1; SMN2 (0.42) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL11585929 | 0.74 | NR4A1 (0.61) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| SCHEMBL9614463 | 0.74 | NR4A1 (0.65) | PLK1NR4A1NR4A2NR4A3MMP3 | |
| Dimethylamine SCHEMBL26099895 | 0.74 | PLK1 (0.62) | PLK1NR4A1NR4A2NR4A3MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228082-A | FUNGICIDES OR CHEMICAL INTERMIDIATES FOR 1,2,4-TRIAZINONE HERBICIDES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-10-14 | — | — | US | disclosed |
| US-4224226-A | FUNGICIDES BY CONDENSING AN ACYL CYANIDE WITH EITHER A TERTIARY ALCOHOL OR AN ALKENE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-23 | — | — | US | disclosed |