Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11477019 | 0.99 | OPRM1 (0.43) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| SCHEMBL11477972 | 0.85 | HTR1A (0.41) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| SCHEMBL11253111 | 0.85 | HTR1A (0.43) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| Hydrochloric Acid SCHEMBL11476881 | 0.84 | HTR1A (0.43) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| SCHEMBL11501244 | 0.84 | HTR1A (0.36) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| SCHEMBL11477520 | 0.84 | OPRM1 (0.63) | OPRM1SMN1; SMN2 | |
| Bromide SCHEMBL11427829 | 0.84 | HTR1A (0.42) | OPRM1HTR1AHTR3ASIRT1SLC6A9 | |
| SCHEMBL11477977 | 0.84 | SMN1; SMN2 (0.46) | OPRM1SLC6A9ALDH1A1LMNAATM | |
| SCHEMBL11478484 | 0.82 | OPRM1 (0.47) | OPRM1ALDH1A1KMT2AMEN1LMNA | |
| Bromide SCHEMBL11487097 | 0.82 | SMN1; SMN2 (0.45) | OPRM1SLC6A9ALDH1A1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | claimed |
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |