Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477282 | 0.84 | OPRM1 (0.44) | HTR1AHTR3AOPRM1SIRT1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11477019 | 0.83 | OPRM1 (0.43) | HTR1AHTR3AOPRM1SIRT1KMT2A | |
| SCHEMBL11253111 | 0.82 | HTR1A (0.43) | HTR1AHTR3AOPRM1SIRT1LMNA | |
| Bromide SCHEMBL11427829 | 0.81 | HTR1A (0.42) | HTR1AHTR3AOPRM1SIRT1LMNA | |
| SCHEMBL11477972 | 0.80 | HTR1A (0.41) | HTR1AHTR3AOPRM1SIRT1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11476881 | 0.79 | HTR1A (0.43) | HTR1AHTR3AOPRM1SIRT1ALDH1A1 | |
| SCHEMBL11477520 | 0.76 | OPRM1 (0.63) | OPRM1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL11490107 | 0.74 | OPRM1 (0.60) | OPRM1 | |
| SCHEMBL11249097 | 0.74 | HTR1A (0.46) | HTR1AHTR3AOPRM1SIRT1SMN1; SMN2 | |
| Bromide SCHEMBL11427938 | 0.73 | HTR1A (0.45) | HTR1AHTR3AOPRM1SIRT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |