Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86299 | 0.87 | MAOA (0.50) | LMNAKMT2AALDH1A1TDP1MAPT | |
| Ethylene SCHEMBL7815591 | 0.84 | MAOA (0.47) | LMNAKMT2AALDH1A1TDP1MAPT | |
| SCHEMBL11467914 | 0.81 | MEN1 (0.53) | SMN1; SMN2TP53LMNAKMT2AMEN1 | |
| SCHEMBL11457114 | 0.81 | MEN1 (0.53) | SMN1; SMN2TP53LMNAKMT2AMEN1 | |
| SCHEMBL11456351 | 0.78 | AKR1B1 (0.46) | SMN1; SMN2TP53LMNAKMT2AMEN1 | |
| SCHEMBL11467888 | 0.75 | HTR1A (0.56) | SMN1; SMN2TP53LMNAKMT2AMEN1 | |
| SCHEMBL11467896 | 0.74 | S100A4 (0.50) | LMNAKMT2ANPC1PKMRAB9A | |
| SCHEMBL11456433 | 0.74 | AKR1B1 (0.57) | ALOX15KDM4ETSHRALDH1A1HSD17B10 | |
| SCHEMBL10320848 | 0.74 | AKR1B1 (0.54) | ALOX15KDM4ETSHRALDH1A1HSD17B10 | |
| SCHEMBL11467898 | 0.74 | MAPT (0.40) | SMN1; SMN2TP53LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230703-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |