Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.74 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 4/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | NQO1 | P15559 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082203 | 0.89 | ESR1 (0.82) | ERAP1NOX4ESR1ESR2KDM4E | |
| SCHEMBL31675834 | 0.89 | ESR1 (0.82) | ERAP1NOX4ESR1ESR2KDM4E | |
| SCHEMBL11477219 | 0.88 | ERAP1 (0.61) | ERAP1NOX4ESR1ESR2KDM4E | |
| SCHEMBL3366067 | 0.86 | ESR1 (0.88) | ERAP1NOX4ESR1ESR2KDM4E | |
| SCHEMBL8934513 | 0.86 | ESR1 (0.88) | ERAP1NOX4ESR1ESR2KDM4E | |
| SCHEMBL1608015 | 0.85 | ERAP1 (1.00) | ERAP1ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL669375 | 0.83 | MAOB (0.70) | ERAP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29466790 | 0.83 | MAOB (0.70) | ERAP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5141444 | 0.81 | MAOB (0.71) | ERAP1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7165990 | 0.81 | ESR1 (0.74) | ERAP1NOX4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |