Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 12/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 12/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 10/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL28341013 | 0.82 | TGFBR1 (0.33) | TGFBR1RXFP1 | |
| SCHEMBL1903516 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNA4CHRNB4TGFBR1CHRNA3 | |
| SCHEMBL2467198 | 0.81 | TGFBR1 (0.34) | TGFBR1RXFP1 | |
| SCHEMBL366427 | 0.79 | CYP2D6 (0.52) | TGFBR1RXFP1NPC1RAB9AKMT2A | |
| SCHEMBL3734949 | 0.77 | GAA (0.44) | TGFBR1RXFP1NPC1RAB9AKMT2A | |
| SCHEMBL12642676 | 0.77 | TGFBR1 (0.39) | TGFBR1RXFP1KMT2ATSHRCYP2D6 | |
| SCHEMBL16097 | 0.77 | TGFBR1 (0.39) | TGFBR1RXFP1KMT2ATSHRCYP2D6 | |
| SCHEMBL9289423 | 0.77 | TGFBR1 (0.39) | TGFBR1RXFP1KMT2ATSHRCYP2D6 | |
| Fluoride SCHEMBL8583071 | 0.77 | CHRNB2 (0.46) | CHRNB2CHRNA4CHRNB4TGFBR1CHRNA3 | |
| SCHEMBL12286434 | 0.76 | RXFP1 (0.37) | TGFBR1RXFP1TSHRCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724288-B2 | Copolymers useful as rheology modifiers and home and personal care compositions comprising said copolymers | BASF SE (DE) | 2017-08-08 | — | — | US | claimed |
| WO-2017012963-A1 | POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF | BASF SE (DE) | 2017-01-26 | — | — | WO | claimed |
| US-20160338939-A1 | COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS | BASF SE (DE) | 2016-11-24 | — | — | US | claimed |
| EP-1958610-B1 | Method of permanently deforming keratinous fibres including an application step involving an oxidising composition containing a cationic thickening polymer | ORÉAL L (FR) | 2016-08-10 | — | — | EP | claimed |
| EP-1987083-B1 | POLYMERIZABLE SILICONE COPOLYOL MACROMERS AND POLYMERS MADE THEREFROM | LUBRIZOL ADVANCED MAT INC (US) | 2014-08-27 | — | — | EP | claimed |
| US-8796484-B2 | Polymerizable silicone copolyol macromers and polymers made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-08-05 | — | — | US | claimed |
| EP-2328547-B1 | COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2014-03-05 | — | — | EP | claimed |
| US-20130137844-A1 | Polymerizable Silicone Copolyol Macromers And Polymers Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2013-05-30 | — | — | US | claimed |
| EP-1988873-B1 | POLYMERS CONTAINING SILICONE COPOLYOL MACROMERS AND PERSONAL CARE COMPOSITIONS CONTAINING SAME | LUBRIZOL ADVANCED MAT INC (US) | 2013-01-09 | — | — | EP | claimed |
| US-8044156-B2 | Polymers can swell upon both acidification and alkylation; thickeners, emulsifiers, stabilizers, suspending agents, film formers, conditioners, health care; rheology; 2-(N,N-dialkylamino)alkyl (meth)acrylate monomers; antistatic agents, preservatives, microbiocides; cosmetics; smooth texture | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2011-10-25 | — | — | US | claimed |
| EP-1987083-A2 | POLYMERIZABLE SILICONE COPOLYOL MACROMERS AND POLYMERS MADE THEREFROM | Lubrizol Advanced Materials, Inc. (US) | 2008-11-05 | — | — | EP | claimed |
| US-7378479-B2 | Multi-purpose polymers, methods and compositions | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2008-05-27 | — | — | US | claimed |
| WO-2007101048-A2 | POLYMERIZABLE SILICONE COPOLYOL MACROMERS AND POLYMERS MADE THEREFROM | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070203311-A1 | Polymerizable Silicone Copolymer Macromers and Polymers Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2007-08-30 | — | — | US | claimed |
| EP-1298166-B1 | RUBBER COMPOSITION | JSR CORP (JP) | 2007-02-21 | — | — | EP | claimed |
| EP-1581568-B1 | MULTI-PURPOSE POLYMERS, METHODS AND COMPOSITIONS | NOVEON IP HOLDINGS CORP (US) | 2006-07-05 | — | — | EP | claimed |
| EP-1581568-A2 | MULTI-PURPOSE POLYMERS, METHODS AND COMPOSITIONS | Noveon IP Holdings Corp. (US) | 2005-10-05 | — | — | EP | claimed |
| WO-2004024779-A2 | MULTI-PURPOSE CATIONIC AND ASSOCIATIVE POLYMERS AND COMPOSITIONS CONTAINING THEM AND THEIR METHOD OF PREPARATION | NOVEON IP HOLDINGS CORP. (US) | 2004-03-25 | — | — | WO | claimed |
| US-20040052746-A1 | Multi-purpose polymers, methods and compositions | LUBRIZOL ADVANCED MATERIALS, INC. | 2004-03-18 | — | — | US | claimed |
| EP-0607962-B1 | Photosensitive resin composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-07-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160338939-A1 | COPOLYMERS USEFUL AS RHEOLOGY MODIFIERS AND HOME AND PERSONAL CARE COMPOSITIONS COMPRISING SAID COPOLYMERS | PHLPP1, PHLPP2, F12 | CHRNB2 4190/4885CHRNA4 4136/4885CHRNB4 4106/4885 |
| US-20040052746-A1 | Multi-purpose polymers, methods and compositions | PLOD3, PARN, PARG | CHRNB2 4416/4885CHRNA4 4672/4885CHRNB4 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.