Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471888 | 0.98 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1KDM4ETDP1RAB9A | |
| Oxalic Acid SCHEMBL11486423 | 0.86 | KDM2B (0.43) | SIGMAR1SLC18A3 | |
| SCHEMBL11470563 | 0.83 | OPRL1 (0.43) | SIGMAR1SLC18A3 | |
| Oxalic Acid SCHEMBL11490220 | 0.82 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KDM4ETDP1SLC18A3 | |
| SCHEMBL11479599 | 0.80 | OPRK1 (0.50) | ALDH1A1KDM4ETDP1SLC18A3GAA | |
| SCHEMBL11475284 | 0.80 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1KDM4ESLC18A3SMN1; SMN2 | |
| Oxalic Acid SCHEMBL11490223 | 0.79 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1KDM4ETDP1SLC18A3 | |
| Oxalic Acid SCHEMBL11485566 | 0.79 | OPRM1 (0.46) | SIGMAR1ALDH1A1KDM4EADRA1ASLC18A3 | |
| SCHEMBL11475291 | 0.77 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1KDM4ESLC18A3SMN1; SMN2 | |
| SCHEMBL11478119 | 0.77 | OPRM1 (0.48) | SIGMAR1ALDH1A1ADRA1ASLC18A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198417-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |