Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476689 | 0.85 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL2331968 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL1194406 | 0.75 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL2435773 | 0.74 | RAB9A (0.61) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL204571 | 0.73 | MAPT (0.78) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL30267589 | 0.73 | MAPT (0.78) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL30785527 | 0.73 | MAPT (0.78) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL12278184 | 0.72 | CA2 (0.52) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| SCHEMBL23546581 | 0.71 | MAPT (0.62) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL7056525 | 0.71 | MAPT (0.75) | ALDH1A1SMN1; SMN2HPGDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221806-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0005141-A1 | Benzothiopyran derivatives, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-11-14 | — | — | EP | disclosed |