Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL1148101 | 0.77 | FKBP1A (0.51) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL1148098 | 0.74 | FKBP1A (0.47) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL1148153 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNAMAPTRAB9A | |
| SCHEMBL19357201 | 0.71 | LMNA (0.66) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL20866527 | 0.70 | RAB9A (0.81) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL15005300 | 0.68 | FKBP1A (0.59) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4720540 | 0.68 | MAPT (0.59) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL12359393 | 0.68 | FKBP1A (1.00) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL23732382 | 0.68 | FKBP1A (0.57) | FKBP1AALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4176542 | 0.67 | SMN1; SMN2 (0.51) | ALDH1A1HPGDMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | disclosed |
| EP-1660441-A2 | N-SULFONYL-ALPHA-AMINO-ACID DERIVATIVES | Syngenta Participations AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021490-A2 | N-SULFONYL-α-AMINO-ACID DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | C3AR1, GLRA1, C5AR1 | FKBP1A 3746/4885ALDH1A1 1621/4885HPGD 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.