SCHEMBL1148147

SCHEMBL1148147

CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(OS(=O)(=O)c2ccccn2)=NN1c1ncccc1Cl)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.38
SLC6A9 P48067 4/20 0.36
IDO1 P14902 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HMOX1 P09601 1/20 0.33
MALT1 Q9UDY8 4/20 0.33
RBP4 P02753 2/20 0.33
GRM4 Q14833 1/20 0.33
MRGPRX1 Q96LB2 1/20 0.33
POLB P06746 1/20 0.32
NAMPT P43490 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148545 0.90 F10 (0.38) F10IDO1NPC1RAB9AMALT1
SCHEMBL590692 0.90 F10 (0.37) F10IDO1NPC1RAB9AMALT1
SCHEMBL1148604 0.90 MALT1 (0.37) F10SLC6A9IDO1MALT1NAMPT
SCHEMBL1148202 0.89 IDO1 (0.34) F10SLC6A9IDO1MALT1NAMPT
SCHEMBL1148471 0.89 HTT (0.41) F10IDO1MALT1POLB
SCHEMBL1148359 0.88 F10 (0.35) F10IDO1NPC1RAB9AMALT1
SCHEMBL1148408 0.88 F10 (0.36) F10IDO1NPC1RAB9ARBP4
SCHEMBL1148144 0.87 F10 (0.37) F10SLC6A9IDO1NPC1RAB9A
SCHEMBL1148200 0.86 SLC6A9 (0.36) SLC6A9IDO1NPC1RAB9AHMOX1
SCHEMBL1148683 0.86 SLC6A9 (0.40) F10SLC6A9MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 F10 934/4885SLC6A9 3705/4885IDO1 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.