SCHEMBL1148604

SCHEMBL1148604

Cc1cc(Cl)cc(C(=O)NC(C)C2CC2)c1NC(=O)C1CC(OS(=O)(=O)c2ccccn2)=NN1c1ncccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 9/20 0.37
IDO1 P14902 1/20 0.34
DRD4 P21917 1/20 0.34
SLC6A9 P48067 4/20 0.33
CCR8 P51685 1/20 0.33
F10 P00742 1/20 0.32
NAMPT P43490 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148202 0.93 IDO1 (0.34) MALT1IDO1SLC6A9F10NAMPT
SCHEMBL592178 0.92 MALT1 (0.40) MALT1IDO1DRD4CCR8F10
SCHEMBL590218 0.91 MALT1 (0.37) MALT1IDO1DRD4CCR8F10
SCHEMBL1148325 0.91 MALT1 (0.37) MALT1IDO1CCR8F10NAMPT
SCHEMBL1148147 0.90 F10 (0.38) MALT1IDO1SLC6A9F10NAMPT
SCHEMBL1148161 0.90 MALT1 (0.38) MALT1DRD4
SCHEMBL1148185 0.89 TSHR (0.37) MALT1IDO1CCR8F10
SCHEMBL1148277 0.88 MALT1 (0.35) MALT1IDO1DRD4CCR8
SCHEMBL1148600 0.88 MALT1 (0.36) MALT1IDO1DRD4CCR8F10
SCHEMBL1148301 0.88 MALT1 (0.35) MALT1IDO1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 MALT1 3967/4885IDO1 288/4885DRD4 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.