SCHEMBL1148161

SCHEMBL1148161

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)C1CC(OS(=O)(=O)c2ccccn2)=NN1c1ncccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 14/20 0.38
DRD4 P21917 1/20 0.34
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
PPARD Q03181 1/20 0.31
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148234 0.91 MALT1 (0.35) MALT1
SCHEMBL1148400 0.90 MALT1 (0.37) MALT1DRD4
SCHEMBL1148148 0.90 MALT1 (0.38) MALT1DRD4TP53MAPTPPARD
SCHEMBL1148604 0.90 MALT1 (0.37) MALT1DRD4
SCHEMBL1148149 0.88 MALT1 (0.37) MALT1
SCHEMBL1148390 0.87 MALT1 (0.36) MALT1TP53MAPT
SCHEMBL1148159 0.87 MALT1 (0.37) MALT1DRD4TP53MAPTPPARD
SCHEMBL1148275 0.86 MALT1 (0.36) MALT1TP53MAPT
SCHEMBL13242829 0.85 MALT1 (0.42) MALT1DRD4MAPTPPARD
SCHEMBL13356325 0.85 MALT1 (0.44) MALT1DRD4GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 MALT1 3967/4885DRD4 3861/4885TP53 2446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.