Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478690 | 0.84 | L3MBTL1 (0.40) | THRBATML3MBTL1TSHRHCRTR2 | |
| SCHEMBL25759294 | 0.83 | ALDH1A1 (0.49) | THRBATML3MBTL1TSHRHCRTR2 | |
| SCHEMBL9139269 | 0.82 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL23795169 | 0.82 | ALDH1A1 (0.38) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28198173 | 0.82 | HSD17B10 (0.47) | L3MBTL1TSHRHCRTR2ALDH1A1 | |
| SCHEMBL7527261 | 0.82 | TSHR (0.45) | THRBATML3MBTL1TSHRHCRTR2 | |
| SCHEMBL11560770 | 0.80 | FKBP1A (0.37) | THRBATML3MBTL1TSHRALDH1A1 | |
| SCHEMBL27412105 | 0.78 | HPGD (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL3122087 | 0.77 | ALDH1A1 (0.39) | THRBATML3MBTL1TSHRALDH1A1 | |
| SCHEMBL11564117 | 0.77 | CHRM2 (0.43) | THRBATML3MBTL1HCRTR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234484-A | FROM ALKOXYLATED CYCLIC AMIDES USING AS A CATALYST A QUATERNARY AMMONIUM OR ALKALI METAL SALT OF TETRAFLUOROBORIC OR HEXAFLUOROPHOSPHORIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |