SCHEMBL1148434

SCHEMBL1148434

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)C1CC(OS(=O)(=O)c2ccncc2)=NN1c1ncccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 8/20 0.35
GPR6 P46095 5/20 0.32
TYK2 P29597 1/20 0.30
KMT2A Q03164 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148316 0.93 MALT1 (0.34) MALT1KMT2APPARG
SCHEMBL1148148 0.91 MALT1 (0.38) MALT1
SCHEMBL1148188 0.91 GPR17 (0.33) MALT1GPR6KMT2A
SCHEMBL1148234 0.90 MALT1 (0.35) MALT1GPR6TYK2KMT2A
SCHEMBL1148432 0.89 MALT1 (0.34) MALT1GPR6
SCHEMBL1148615 0.88 F2 (0.35) MALT1KMT2A
SCHEMBL1148420 0.87 F2 (0.35) MALT1KMT2A
SCHEMBL9290062 0.86 MALT1 (0.40) MALT1GPR6TYK2KMT2A
SCHEMBL1148490 0.85 MALT1 (0.40) MALT1GPR6TYK2KMT2A
SCHEMBL1148315 0.85 MALT1 (0.36) MALT1GPR6KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 MALT1 3967/4885GPR6 4682/4885TYK2 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.