Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE8A | O60658 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245310 | 0.88 | EEF2K (0.45) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL11488120 | 0.86 | KDM4E (0.46) | MEN1KMT2ALMNAADORA1KDM4E | |
| SCHEMBL11486201 | 0.86 | KDM4E (0.46) | MEN1KMT2ALMNAADORA1KDM4E | |
| SCHEMBL11488105 | 0.86 | CNR1 (0.47) | MEN1KMT2ALMNAADORA1KDM4E | |
| SCHEMBL11083105 | 0.86 | KDM4E (0.60) | MEN1KMT2ALMNAADORA1KDM4E | |
| SCHEMBL11080468 | 0.85 | LMNA (0.48) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL11486236 | 0.85 | KDM4E (0.59) | MEN1KMT2ALMNAADORA1KDM4E | |
| SCHEMBL11636233 | 0.85 | LMNA (0.46) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL11234096 | 0.83 | KMT2A (0.44) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL11486422 | 0.82 | LMNA (0.45) | MEN1KMT2ALMNAABCC4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | claimed |
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |