Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083105 | 0.99 | KDM4E (0.60) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11486123 | 0.89 | ALDH1A1 (0.57) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11639605 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7832109 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1LMNAHTTMEN1 | |
| SCHEMBL3522404 | 0.86 | LMNA (0.64) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11637475 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8141322 | 0.86 | ALDH1A1 (0.61) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11167153 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11083016 | 0.85 | L3MBTL1 (0.50) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2084677 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | claimed |
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |