Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149230 | 0.85 | NPC1 (0.43) | L3MBTL1TDP1NPC1RAB9AMEN1 | |
| SCHEMBL11476560 | 0.77 | RAB9A (0.49) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11147048 | 0.71 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11158867 | 0.71 | MEN1 (0.47) | TSHRL3MBTL1TDP1BCHEALOX15 | |
| Hydrochloric Acid SCHEMBL11152602 | 0.70 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10919254 | 0.69 | NPC1 (0.47) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11148522 | 0.69 | ALDH1A1 (0.43) | TDP1HRH2HRH1NPC1RAB9A | |
| SCHEMBL2399420 | 0.68 | NPC1 (0.57) | TSHRL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL8575841 | 0.67 | ALDH1A1 (0.44) | L3MBTL1TDP1NPC1RAB9AMEN1 | |
| SCHEMBL11728742 | 0.66 | MAOB (0.54) | TSHRL3MBTL1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207237-A | Preparation of pyrrole-2-acetates | MCNEILAB, INC. (US) | 1980-06-10 | — | — | US | disclosed |