Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148698 | 0.81 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148726 | 0.80 | ALDH1A1 (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148637 | 0.78 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148450 | 0.75 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL13983495 | 0.74 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL13983498 | 0.74 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147910 | 0.72 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148574 | 0.72 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148383 | 0.72 | MAPT (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148650 | 0.72 | KDM4E (0.40) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051416-A2 | COMPOUNDS THAT INHIBIT THE ACTIVITY OF HSP90 FOR TREATING INFECTIONS | SYNTA PHARMACEUTICALS CORP. (US) | 2008-05-02 | — | — | WO | disclosed |