Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494252 | 0.91 | TSHR (0.43) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL11606556 | 0.89 | MAPK1 (0.38) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL11485866 | 0.85 | DRD2 (0.46) | MEN1KMT2A | |
| SCHEMBL11603164 | 0.84 | AKT1 (0.40) | MEN1KMT2A | |
| SCHEMBL11494471 | 0.84 | HTT (0.38) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL11486667 | 0.84 | POLB (0.38) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL11490552 | 0.83 | SLC6A3 (0.38) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL19993113 | 0.83 | HTT (0.41) | MITFLMNACNR1CNR2GPR35 | |
| SCHEMBL13792137 | 0.83 | ALDH1A1 (0.41) | HTTALDH1A1HPGDCYP17A1 | |
| SCHEMBL11496175 | 0.81 | SLC6A4 (0.45) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |