Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11486149 | 0.98 | SMN1; SMN2 (0.42) | OPRL1SIGMAR1SMN1; SMN2MAPTATM | |
| SCHEMBL11490756 | 0.95 | OPRL1 (0.47) | OPRL1SIGMAR1OPRM1OPRK1OPRD1 | |
| SCHEMBL11476409 | 0.89 | SLC18A3 (0.41) | OPRL1SIGMAR1SMN1; SMN2MAPTATM | |
| Oxalic Acid SCHEMBL11490183 | 0.87 | KDM4E (0.40) | OPRL1SIGMAR1SMN1; SMN2MAPTATM | |
| SCHEMBL11487769 | 0.86 | OPRM1 (0.51) | OPRM1OPRK1LMNAMEN1KMT2A | |
| SCHEMBL11481965 | 0.86 | OPRM1 (0.48) | SMN1; SMN2MAPTATMOPRM1OPRK1 | |
| Bromide SCHEMBL11474247 | 0.85 | OPRM1 (0.50) | OPRM1OPRK1LMNAMEN1KMT2A | |
| SCHEMBL11483187 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTATMOPRM1OPRK1 | |
| Oxalic Acid SCHEMBL11487121 | 0.80 | KDM4E (0.50) | SMN1; SMN2MAPTOPRM1OPRK1ALDH1A1 | |
| SCHEMBL11478460 | 0.78 | USP30 (0.38) | SMN1; SMN2MAPTATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | claimed |