Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487147 | 0.95 | OPRL1 (0.42) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| Oxalic Acid SCHEMBL11486149 | 0.93 | SMN1; SMN2 (0.42) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11476409 | 0.84 | SLC18A3 (0.41) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11481965 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1OPRD1 | |
| Oxalic Acid SCHEMBL11490183 | 0.82 | KDM4E (0.40) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11487769 | 0.81 | OPRM1 (0.51) | OPRM1OPRK1OPRD1 | |
| Bromide SCHEMBL11474247 | 0.81 | OPRM1 (0.50) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11483187 | 0.79 | SMN1; SMN2 (0.46) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11478230 | 0.79 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| Oxalic Acid SCHEMBL11487121 | 0.77 | KDM4E (0.50) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198419-A | Phenylthiophenylpiperidines | AMERICAN HOECHST CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |