Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890403 | 0.88 | BRD4 (0.36) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL10542287 | 0.85 | MTNR1A (0.38) | ITGB1 | |
| SCHEMBL11363297 | 0.85 | KMT2A (0.32) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL10884861 | 0.80 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8014019 | 0.79 | KDM4E (0.38) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8019417 | 0.79 | KDM4E (0.38) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11538730 | 0.77 | KMT2A (0.34) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11542905 | 0.76 | ALDH1A1 (0.32) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8604220 | 0.76 | KLK7 (0.33) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL9443885 | 0.76 | MEN1 (0.35) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200572-A | Substituted azetidinones | SMITHKLINE CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |