Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 11/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 11/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489437 | 0.93 | LPAR1 (0.42) | PARP10LPAR1LPAR5MMP14FAAH | |
| SCHEMBL11487885 | 0.90 | PARP10 (0.43) | PARP10LPAR1LPAR5MMP14DAO | |
| SCHEMBL11481145 | 0.88 | HSPB1 (0.41) | FAAH | |
| SCHEMBL11491253 | 0.86 | XIAP (0.41) | LPAR1LPAR5MMP14 | |
| SCHEMBL11480169 | 0.85 | LTA4H (0.35) | MMP1MMP13 | |
| SCHEMBL11485797 | 0.84 | LTA4H (0.44) | — | |
| SCHEMBL11486056 | 0.81 | HSPB1 (0.40) | LPAR1LPAR5FAAH | |
| SCHEMBL11489854 | 0.80 | PARP10 (0.47) | PARP10LPAR1LPAR5MMP14FAAH | |
| SCHEMBL11478348 | 0.79 | LPAR1 (0.38) | LPAR1LPAR5MMP14 | |
| SCHEMBL11479694 | 0.77 | MMP13 (0.38) | FAAHMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196215-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4115456-A | Alkyne compounds and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-19 | — | — | US | disclosed |