Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471482 | 0.81 | DPP7 (0.33) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11479666 | 0.79 | ADORA2A (0.43) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11472448 | 0.77 | CYP2C9 (0.35) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11379771 | 0.74 | MAPT (0.43) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11481166 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11471483 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL11488033 | 0.73 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTCYP3A4BLMPMP22 | |
| SCHEMBL17619941 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2MAPTCYP3A4BLMATM | |
| SCHEMBL6233600 | 0.70 | ACHE (0.39) | — | |
| SCHEMBL11488355 | 0.70 | KDR (0.42) | SMN1; SMN2MAPTCYP3A4LMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235995-A | BACTERIOCIDES, PARASITICIDES, HERBICIDES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4066776-A | Anti-bacterial compositions containing certain 3-nitropyrazoles | ELI LILLY AND COMPANY (US) | 1978-01-03 | — | — | US | disclosed |