Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | EEF2K | O00418 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | EEF2 | P13639 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427537 | 0.81 | ADORA2A (0.49) | ACHEEEF2KADORA2AADORA1L3MBTL1 | |
| SCHEMBL174293 | 0.74 | ADORA2A (0.45) | EEF2KADORA2AADORA1L3MBTL1RCE1 | |
| SCHEMBL17619950 | 0.73 | ACHE (0.33) | ACHE | |
| SCHEMBL2076844 | 0.71 | L3MBTL1 (0.40) | EEF2KADORA2AADORA1L3MBTL1PARP1 | |
| SCHEMBL11488352 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL2076282 | 0.70 | ACHE (0.39) | ACHEEEF2KADORA2AADORA1L3MBTL1 | |
| SCHEMBL27890487 | 0.70 | ADORA2A (0.40) | ACHEADORA2AADORA1L3MBTL1 | |
| SCHEMBL6238381 | 0.68 | ACHE (0.67) | ACHEL3MBTL1 | |
| SCHEMBL2076854 | 0.68 | KDR (0.48) | — | |
| SCHEMBL14808474 | 0.67 | JAK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534713-A1 | ALKYL-SUBSTITUTED PYRAZOLOPYRIMIDINES | Bayer HealthCare AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| EP-1534711-A1 | PHENYL-SUBSTITUTED PYRAZOLOPYRIMIDINES | Bayer HealthCare AG (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004026876-A1 | ALKYL-SUBSTITUTED PYRAZOLOPYRIMIDINES | BAYER HEALTHCARE AG (DE) | 2004-04-01 | — | — | WO | disclosed |
| WO-2004018474-A1 | PHENYL-SUBSTITUTED PYRAZOLOPYRIMIDINES | BAYER HEALTHCARE AG (DE) | 2004-03-04 | — | — | WO | disclosed |