Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.70 |
| ▸ | BLM | P54132 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.70 |
| ▸ | THPO | P40225 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040669 | 0.95 | KDM4E (0.60) | KDM4ETDP1BLMMAPTADRB2 | |
| Racepinephrine SCHEMBL7722144 | 0.91 | KDM4E (0.69) | KDM4ETDP1BLMMAPTADRB2 | |
| SCHEMBL23318541 | 0.86 | ADRB2 (0.57) | KDM4ETDP1BLMMAPTADRB2 | |
| SCHEMBL7272101 | 0.85 | KDM4E (0.62) | KDM4ETDP1BLMMAPTADRB2 | |
| Racepinephrine SCHEMBL4406973 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 | |
| L-Adrenaline SCHEMBL20608410 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 | |
| Racepinephrine SCHEMBL40742 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 | |
| Epinephrine SCHEMBL40741 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 | |
| Epinephrine SCHEMBL29457688 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 | |
| Racepinephrine SCHEMBL29587492 | 0.83 | KDM4E (1.00) | KDM4ETDP1BLMMAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233309-A | Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives | TEIJIN LIMITED (JP) | 1980-11-11 | — | — | US | disclosed |