Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | DRD3 | P35462 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040669 | 0.90 | KDM4E (0.60) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL23318543 | 0.89 | ADRB2 (0.57) | ADRB2KDM4ETDP1HIF1AMAPT | |
| Dibutepinephrine SCHEMBL20141839 | 0.89 | HIF1A (0.69) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL7272101 | 0.86 | KDM4E (0.62) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL11488487 | 0.86 | KDM4E (0.70) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL7394383 | 0.84 | ADRB2 (0.43) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL18740836 | 0.84 | KDM4E (0.57) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL10481814 | 0.83 | HIF1A (0.81) | ADRB2KDM4ETDP1HIF1AMAPT | |
| SCHEMBL31748897 | 0.83 | HIF1A (0.81) | ADRB2KDM4ETDP1HIF1AMAPT | |
| Hydrochloric Acid SCHEMBL9344942 | 0.82 | BLM (0.65) | ADRB2KDM4ETDP1HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128511-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | AQUESTIVE THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| WO-2021087359-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | AQUESTIVE THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128511-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | ADRA2C, ADRB3, ADRA2B | ADRB2 5/4885KDM4E 3454/4885TDP1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.