Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222134 | 0.80 | LMNA (0.44) | SMN1; SMN2LMNARAB9ANPC1TP53 | |
| SCHEMBL4055814 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNARAB9ANPC1TP53 | |
| SCHEMBL22289535 | 0.76 | EPHX1 (0.45) | HTTLMNARAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL27355891 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL9373413 | 0.74 | LMNA (0.53) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL10347562 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2LMNARAB9ANPC1TP53 | |
| SCHEMBL10985519 | 0.74 | SMN1; SMN2 (0.83) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL18519252 | 0.73 | HPGD (0.53) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL8388703 | 0.73 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL249336 | 0.73 | EHMT2 (0.47) | SMN1; SMN2LMNARAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4203897-A | Penam derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-05-20 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |