Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172656 | 0.84 | EHMT2 (0.48) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL27355891 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL10347562 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL11488552 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL11222134 | 0.78 | LMNA (0.44) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL249336 | 0.77 | EHMT2 (0.47) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL8794735 | 0.75 | HPGD (0.67) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| Propionic Acid SCHEMBL28700286 | 0.74 | EHMT2 (0.63) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL1607377 | 0.74 | LMNA (0.51) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL8619200 | 0.73 | HPGD (0.57) | SMN1; SMN2KMT2AMEN1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076673-A2 | LIGAND CONJUGATED THERMOTHERAPY SUSCEPTORS AND METHODS FOR PREPARING SAME | ADURO BIOTECH (US) | 2009-06-18 | — | — | WO | disclosed |