SCHEMBL249336

SCHEMBL249336

NC(=O)NSc1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.47
EHMT1 Q9H9B1 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
KMT2A Q03164 3/20 0.45
PKM P14618 3/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 7/20 0.45
HPGD P15428 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
POLB P06746 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.40
GAA P10253 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10347562 0.83 ALDH1A1 (0.50) EHMT2EHMT1APOBEC3GKMT2APKM
Hydrochloric Acid SCHEMBL27355891 0.80 ALDH1A1 (0.49) EHMT2EHMT1APOBEC3GKMT2APKM
SCHEMBL11222134 0.79 LMNA (0.44) EHMT2EHMT1APOBEC3GKMT2APKM
SCHEMBL4055814 0.77 SMN1; SMN2 (0.49) KMT2APKMMEN1ALDH1A1HPGD
SCHEMBL11035157 0.76 P2RX7 (0.39) KMT2APKMALDH1A1HPGDSMN1; SMN2
SCHEMBL3070731 0.75 EHMT2 (0.52) EHMT2EHMT1APOBEC3GKMT2APKM
Carbamic Acid SCHEMBL16975015 0.75 EHMT2 (0.71) EHMT2EHMT1APOBEC3GKMT2APKM
SCHEMBL3075428 0.74 EHMT2 (0.56) EHMT2EHMT1APOBEC3GKMT2APKM
SCHEMBL28747749 0.74 PLAU (0.41) KMT2APKMMEN1SMN1; SMN2MAPT
SCHEMBL11488552 0.73 SMN1; SMN2 (0.49) KMT2APKMMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3884921-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-07-02 EP claimed
EP-3884922-B1 DENTAL POLYMERIZABLE COMPOSITION G C DENTAL IND CORP (JP) 2025-06-18 EP claimed
CN-120025709-A High-adhesion-degree water-based ink applied to PET film printing and preparation method thereof 潍坊长青塑胶有限公司 2025-05-23 CN claimed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-112946157-B Application of fluorescent thiourea derivatization reagent in detection of 3-chloro-1, 2-propanediol 武汉轻工大学 2023-10-27 CN claimed
US-11571368-B2 Dental polymerizable composition GC CORPORATION (JP) 2023-02-07 US claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-112946157-A Application of fluorescent thiourea derivatization reagent in 3-chloro-1, 2-propanediol detection 武汉轻工大学 2021-06-11 CN claimed
CN-102993915-A 3PP (Propene Polymer) anti-corrosion epoxy powder primer and preparation method thereof SHANGHAI HAILONG SHINE NEW MATERIALS CO LTD 2013-03-27 CN claimed
EP-4029839-B1 GLASS POWDER AND CHEMICAL POLYMERIZATION INITIATOR G C DENTAL IND CORP (JP) 2026-05-06 EP disclosed
US-20260109712-A1 RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA UNIV MINNESOTA (US) 2026-04-23 US disclosed
US-12569409-B2 Dental polymerizable composition GC CORPORATION (JP) 2026-03-10 US disclosed
EP-4656175-A1 DENTAL CEMENT AND DENTAL CEMENT PREPARATION KIT Tokuyama Dental Corporation (JP) 2025-12-03 EP disclosed
US-12478561-B2 Dental composition and dental restorative kit GC CORPORATION (JP) 2025-11-25 US disclosed
WO-2000049015-A1 PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-24 WO disclosed
WO-2000033837-A2 MYT1 KINASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-06-15 WO disclosed
WO-1999064418-A1 ARYL PYRIDINYL THIAZOLES NOVARTIS AG (CH) 1999-12-16 WO disclosed
CN-1224718-A Thiazole derivatives HOFFMANN LA ROCHE (CH) 1999-08-04 CN disclosed
US-4569976-A PEROXIDE CATALYST AND THIOUREA ACTIVATOR THE KENDALL COMPANY (US) 1986-02-11 US disclosed
US-4224331-A TREATING GASTRIC ULCERS AND REDUCING GASTRIC ACID SECRETION BEECHAM GROUP LIMITED (GB) 1980-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569409-B2 Dental polymerizable composition VCL, ACR, TPO EHMT2 3875/4885EHMT1 2740/4885APOBEC3G 2505/4885
US-20260109712-A1 RIFAMYCINS FOR NONTUBERCULOUS MYCOBACTERIA RIF1, MRPL21, NRDC EHMT2 4059/4885EHMT1 3998/4885APOBEC3G 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.