Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568670 | 0.86 | NPC1 (0.53) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11494664 | 0.85 | RAB9A (0.59) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11489618 | 0.79 | LMNA (0.62) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11565905 | 0.78 | ALDH1A1 (0.57) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11488135 | 0.78 | MAPT (0.52) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11493351 | 0.76 | NOD1 (0.59) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL25062551 | 0.75 | KDM4E (0.60) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11494630 | 0.74 | SMN1; SMN2 (0.51) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11487832 | 0.73 | NPC1 (0.49) | RAB9ANPC1NOD1TNFMITF | |
| SCHEMBL11490257 | 0.73 | NPC1 (0.51) | RAB9ANPC1NOD1TNFMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233309-A | Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives | TEIJIN LIMITED (JP) | 1980-11-11 | — | — | US | disclosed |
| EP-0002392-A2 | 1-substituted-3-acylpyrrole derivatives, process for their preparation and platelet aggregation inhibiting agents containing them | TEIJIN LIMITED (JP) | 1979-06-13 | — | — | EP | disclosed |