Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13874195 | 0.87 | ALDH1A1 (0.53) | MAPTSMN1; SMN2TSHRJAK2JAK1 | |
| SCHEMBL11495957 | 0.83 | CYP4Z1 (0.44) | MAPTSMN1; SMN2TSHRCYP4Z1L3MBTL1 | |
| SCHEMBL2646637 | 0.82 | TSHR (0.60) | MAPTSMN1; SMN2TSHRCYP4Z1L3MBTL1 | |
| SCHEMBL31441301 | 0.82 | TSHR (0.60) | MAPTSMN1; SMN2TSHRCYP4Z1L3MBTL1 | |
| SCHEMBL90470 | 0.81 | CYP3A4 (0.49) | MAPTSMN1; SMN2TSHRCYP4Z1JAK2 | |
| Hydrochloric Acid SCHEMBL90469 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2TSHRCYP4Z1JAK2 | |
| SCHEMBL1558288 | 0.79 | CA2 (0.60) | MAPTSMN1; SMN2TSHRL3MBTL1ALOX15 | |
| SCHEMBL4154916 | 0.79 | CA2 (0.59) | MAPTSMN1; SMN2TSHRNFKB1RAB9A | |
| SCHEMBL11009839 | 0.78 | MAPT (0.42) | MAPTSMN1; SMN2TSHRCYP4Z1JAK2 | |
| SCHEMBL13742793 | 0.78 | MAPT (0.48) | MAPTSMN1; SMN2TSHRCYP4Z1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |