Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.73 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480115 | 0.83 | MAOB (0.62) | MAOBNOX4NQO1KDM4EMAOA | |
| SCHEMBL29466790 | 0.80 | MAOB (0.70) | MAOBNQO1KDM4ETOP1CYP2C9 | |
| SCHEMBL669375 | 0.80 | MAOB (0.70) | MAOBNQO1KDM4ETOP1CYP2C9 | |
| SCHEMBL11480111 | 0.78 | MAOB (0.68) | MAOBNOX4NQO1KDM4ETOP1 | |
| SCHEMBL8934636 | 0.78 | MAOB (0.68) | MAOBNOX4NQO1KDM4ETOP1 | |
| SCHEMBL11480850 | 0.78 | MAOB (0.68) | MAOBNOX4NQO1KDM4ETOP1 | |
| SCHEMBL27790298 | 0.78 | MAOB (0.72) | MAOBNQO1KDM4ECYP2C9LMNA | |
| SCHEMBL28085554 | 0.77 | MAOB (0.80) | MAOBNQO1KDM4ECYP2C9LMNA | |
| SCHEMBL28246100 | 0.77 | NQO1 (0.74) | NQO1KDM4ETOP1CYP2C9LMNA | |
| Xylocoumarol SCHEMBL2111715 | 0.77 | MAOB (0.62) | MAOBNQO1KDM4ECYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |