Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485562 | 0.82 | MAOB (1.00) | MAOBKDM4EMEN1CYP3A4MAPT | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL15676607 | 0.79 | KDM4E (1.00) | KDM4EMEN1CYP3A4MAPTHPGD | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL4285872 | 0.79 | KDM4E (1.00) | KDM4EMEN1CYP3A4MAPTHPGD | |
| 3-Hydroxy-3',4'-Dimethoxyflavone SCHEMBL30139617 | 0.79 | KDM4E (1.00) | KDM4EMEN1CYP3A4MAPTHPGD | |
| SCHEMBL27790298 | 0.77 | MAOB (0.72) | MAOBKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL5423277 | 0.77 | FYN (0.62) | MAOBKDM4EMEN1CYP3A4MAPT | |
| SCHEMBL11489232 | 0.77 | MAOB (0.73) | MAOBKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL669375 | 0.77 | MAOB (0.70) | MAOBKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL29466790 | 0.77 | MAOB (0.70) | MAOBKDM4EMEN1CYP3A4KMT2A | |
| Xylocoumarol SCHEMBL2111715 | 0.76 | MAOB (0.62) | MAOBKDM4EMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801544-A | 3-aryl-4-arylamine-coumarin derivative and preparing method and medical application thereof | 中国药科大学 | 2016-07-27 | — | — | CN | disclosed |