SCHEMBL1149006

SCHEMBL1149006

O=S(=O)(Cl)c1ccc2cc3ccccc3cc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
F2 P00734 2/20 0.46
PRSS1 P07477 2/20 0.46
PRSS2 P07478 2/20 0.46
PRSS3 P35030 2/20 0.46
MCOLN3 Q8TDD5 2/20 0.44
TSHR P16473 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
ATM Q13315 1/20 0.42
CYP19A1 P11511 1/20 0.42
PKM P14618 1/20 0.42
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25642 0.93 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL29391838 0.93 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL27629181 0.91 LMNA (0.61) LMNAALDH1A1HSD17B10TDP1L3MBTL1
Hydrochloric Acid SCHEMBL7566123 0.91 LMNA (0.61) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL2263563 0.89 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL30357699 0.89 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL2263247 0.86 LMNA (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL30615201 0.86 LMNA (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
Toluene SCHEMBL14976648 0.83 LMNA (0.52) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL5082883 0.83 LMNA (0.41) LMNAALDH1A1HSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227625-B2 Composite materials comprising mechanical ligands NANOCORE APS (DK) 2025-02-18 US disclosed
CN-110823855-B Method for rapidly detecting amphetamine drugs in human urine 鄂尔多斯应用技术学院 2023-06-06 CN disclosed
EP-4119598-A1 NANOCOMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS Nanocore ApS (DK) 2023-01-18 EP disclosed
EP-3737711-B1 COMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS NANOCORE APS (DK) 2022-04-06 EP disclosed
EP-3737711-A1 COMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS Nanocore Aps (DK) 2020-11-18 EP disclosed
US-20200354220-A1 COMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS NANOCORE APS (DK) 2020-11-12 US disclosed
US-20200354220-A1 COMPOSITE MATERIALS COMPRISING MECHANICAL LIGANDS NANOCORE APS (DK) 2020-11-12 US disclosed
CN-111868146-A Composite materials comprising mechanical ligands 纳诺科尔有限公司 2020-10-30 CN disclosed
CN-110823855-A Method for rapidly detecting amphetamine drugs in human urine 鄂尔多斯应用技术学院 2020-02-21 CN disclosed
US-8304520-B2 Labeled fusion protein THE UNIVERSITY OF TOKYO (JP) 2012-11-06 US disclosed
EP-0383803-A1 OLIGONUCLEOTIDE-POLYAMIDE CONJUGATES HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) 1990-08-29 EP disclosed
EP-0366685-A1 NUCLEOSIDE DERIVATIVES. FLOREY HOWARD INST (AU) 1990-05-09 EP disclosed
WO-1989003849-A1 OLIGONUCLEOTIDE-POLYAMIDE CONJUGATES HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) 1989-05-05 WO disclosed
WO-1988010264-A1 NUCLEOSIDE DERIVATIVES HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) 1988-12-29 WO disclosed
US-4150051-A N-Cyanosulfonamide compounds CIBA-GEIGY CORPORATION (US) 1979-04-17 US disclosed
US-4128586-A Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols ALLIED CHEMICAL CORPORATION (US) 1978-12-05 US disclosed
US-4080483-A COATINGS, MOLDING MATERIALS, LAMINATION CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4075185-A ADDITION POLYMERIZATION CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 US disclosed
US-3944526-A N-cyanosulfonamide resins and intermediates therefor and products thereof CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed