Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391838 | 0.89 | LMNA (0.63) | LMNAL3MBTL1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL25642 | 0.89 | LMNA (0.63) | LMNAL3MBTL1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27629181 | 0.87 | LMNA (0.61) | LMNAL3MBTL1PKMSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7566123 | 0.87 | LMNA (0.61) | LMNAL3MBTL1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7523945 | 0.83 | L3MBTL1 (0.46) | LMNAL3MBTL1HTTPKMSMN1; SMN2 | |
| SCHEMBL1149006 | 0.83 | LMNA (0.55) | LMNAL3MBTL1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7013575 | 0.81 | CYP2A6 (0.54) | LMNAL3MBTL1HTTPKMSMN1; SMN2 | |
| SCHEMBL28218179 | 0.81 | LMNA (0.50) | LMNAL3MBTL1PKMSMN1; SMN2KAT6A | |
| Toluene SCHEMBL1393755 | 0.81 | ALDH1A1 (0.65) | LMNAL3MBTL1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2263563 | 0.80 | LMNA (0.48) | LMNAL3MBTL1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013076590-A1 | BENZOTHIAZINE COMPOUNDS AS H3 RECEPTOR LIGANDS | OXYGEN HEALTHCARE RESEARCH PVT. LTD (IN) | 2013-05-30 | — | — | WO | disclosed |