SCHEMBL5082883

SCHEMBL5082883

O=S(=O)(Cl)c1ccc2cc(S(=O)(=O)Cl)c(S(=O)(=O)Cl)cc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
MCOLN3 Q8TDD5 2/20 0.33
SNCA P37840 2/20 0.33
TSHR P16473 1/20 0.33
TRPV4 Q9HBA0 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30357699 0.89 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL2263563 0.89 LMNA (0.48) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL2263247 0.86 LMNA (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL30615201 0.86 LMNA (0.46) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL1149006 0.83 LMNA (0.55) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL29391838 0.80 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL25642 0.80 LMNA (0.63) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL29057554 0.79 ALDH1A1 (0.44) LMNAALDH1A1HSD17B10TDP1L3MBTL1
Hydrochloric Acid SCHEMBL7566123 0.78 LMNA (0.61) LMNAALDH1A1HSD17B10TDP1L3MBTL1
SCHEMBL27629181 0.78 LMNA (0.61) LMNAALDH1A1HSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137200-A1 COMPOSITE MEMBRANE WITH SUPPORT COMPRISING POLY(PHENYLENE ETHER) AND AMPHILPHILIC POLYMER; METHOD OF MAKING; AND SEPARATION MODULE THEREOF SABIC Global Technologies B.V. (NL) 2017-03-08 EP disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed