Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814250 | 0.89 | PTGS1 (0.54) | PTGS1ABCC4PTGS2EPHX1APP | |
| SCHEMBL11477693 | 0.87 | PTGS1 (0.58) | PTGS1ABCC4PTGS2 | |
| SCHEMBL11485249 | 0.82 | PTGS1 (0.66) | PTGS1ABCC4PTGS2HDAC3HDAC4 | |
| SCHEMBL11478065 | 0.82 | ABCC4 (0.42) | PTGS1ABCC4 | |
| SCHEMBL11477837 | 0.81 | PTGS2 (0.42) | PTGS1ABCC4PTGS2EPHX1APP | |
| SCHEMBL1915188 | 0.80 | HDAC3 (0.58) | PTGS1PTGS2HDAC3HDAC4HDAC1 | |
| SCHEMBL11487067 | 0.79 | PTGS1 (0.52) | PTGS1ABCC4PTGS2 | |
| SCHEMBL11476605 | 0.78 | PTGS2 (0.42) | PTGS1ABCC4PTGS2EPHX1APP | |
| SCHEMBL11828373 | 0.77 | MAOA (0.53) | — | |
| SCHEMBL9420879 | 0.76 | PTGS1 (0.69) | PTGS1ABCC4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205170-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-05-27 | — | — | US | disclosed |