SCHEMBL9420879

SCHEMBL9420879

CC(C(=O)O)c1ccc2c(c1)Cc1ccccc1O2

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 6/20 0.69
ABCC4 O15439 1/20 0.69
PTGS2 P35354 6/20 0.52
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
OPRK1 P41145 1/20 0.47
PDE4D Q08499 1/20 0.47
ACSL1 P33121 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
FABP2 P12104 1/20 0.43
TSHR P16473 1/20 0.43
AKR1C4 P17516 1/20 0.43
ADRA2B P18089 1/20 0.43
CHRM3 P20309 1/20 0.43
HTR2C P28335 1/20 0.43
DRD3 P35462 1/20 0.43
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11477693 0.89 PTGS1 (0.58) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11814250 0.87 PTGS1 (0.54) PTGS1ABCC4PTGS2MAOAMAOB
SCHEMBL11813936 0.87 PTGS1 (0.54) PTGS1ABCC4PTGS2MAOAMAOB
SCHEMBL4447825 0.87 PTGS1 (0.63) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11339446 0.85 PTGS2 (0.54) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11339262 0.83 PTGS1 (0.61) PTGS1ABCC4PTGS2MEN1KMT2A
SCHEMBL11487067 0.83 PTGS1 (0.52) PTGS1ABCC4PTGS2MEN1KMT2A
SCHEMBL11474926 0.83 PTGS2 (0.54) PTGS1ABCC4PTGS2OPRK1PDE4D
Pranoprofen SCHEMBL26008 0.82 PTGS1 (1.00) PTGS1ABCC4PTGS2OPRK1PDE4D
Pranoprofen SCHEMBL5936565 0.82 PTGS1 (1.00) PTGS1ABCC4PTGS2OPRK1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338852-B1 Process for the carbonylation of arylalkyl halides HOECHST CELANESE CORP (US) 1994-11-30 EP claimed
EP-0338852-A1 Process for the carbonylation of arylalkyl halides HOECHST CELANESE CORPORATION (US) 1989-10-25 EP claimed
CN-118302424-A Dielectric materials based on heteroaromatic extended bismaleimides 默克专利有限公司 2024-07-05 CN disclosed
CN-117279891-A Dielectric materials based on oligomeric amide extended bismaleimides 默克专利股份有限公司 2023-12-22 CN disclosed
CN-117043233-A Dielectric materials based on amide-imide extended bismaleimides 默克专利股份有限公司 2023-11-10 CN disclosed
CN-116529291-A Dielectric materials based on bismaleimides containing carbopol/spiro moieties 默克专利股份有限公司 2023-08-01 CN disclosed
CN-111093971-B Optical laminate, method for producing optical laminate, optical member, and image display device 日东电工株式会社 2022-04-29 CN disclosed
CN-107108943-B Film having void structure bonded through catalytic action and method for producing same 日东电工株式会社 2021-06-11 CN disclosed
CN-107709010-B Laminated film, optical member, and image display device 日东电工株式会社 2021-06-11 CN disclosed
CN-107108944-B Silicone porous body and method for producing same 日东电工株式会社 2021-06-11 CN disclosed
CN-111363472-A Coating and method for producing same 日东电工株式会社 2020-07-03 CN disclosed
CN-107109125-B Coating and method for producing same 日东电工株式会社 2020-05-19 CN disclosed
CN-111093971-A Optical laminate, method for producing optical laminate, optical member, and image display device 日东电工株式会社 2020-05-01 CN disclosed
US-3948949-A ANTIPHOLISTIC MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER (DT) 1976-04-06 US disclosed