Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487067 | 0.91 | PTGS1 (0.52) | PTGS1ABCC4PTGS2AKR1B1MAPT | |
| SCHEMBL9420879 | 0.89 | PTGS1 (0.69) | PTGS1ABCC4PTGS2OPRK1PDE4D | |
| SCHEMBL11490477 | 0.87 | PTGS1 (0.45) | PTGS1ABCC4PTGS2 | |
| SCHEMBL11339262 | 0.83 | PTGS1 (0.61) | PTGS1ABCC4PTGS2MEN1KMT2A | |
| SCHEMBL11478065 | 0.83 | ABCC4 (0.42) | PTGS1ABCC4KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11178212 | 0.82 | HTR1A (0.44) | PTGS1ABCC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11476360 | 0.82 | PTGS1 (0.82) | PTGS1ABCC4PTGS2AKR1B1OPRK1 | |
| SCHEMBL28488032 | 0.82 | PTGS1 (0.61) | PTGS1ABCC4PTGS2AKR1B1MAPT | |
| SCHEMBL29430898 | 0.82 | PTGS1 (0.61) | PTGS1ABCC4PTGS2AKR1B1MAPT | |
| SCHEMBL11339446 | 0.80 | PTGS2 (0.54) | PTGS1ABCC4PTGS2AKR1B1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205170-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-05-27 | — | — | US | disclosed |
| US-4104280-A | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives | SYNTEX (U.S.A.) INC. (US) | 1978-08-01 | — | — | US | disclosed |