SCHEMBL1149136

SCHEMBL1149136

C=CCC(=O)CC(=O)ON(C)C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.41
KDM5C P41229 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233075 0.81 ALDH1A1 (0.31) ALDH1A1LMNA
SCHEMBL12136578 0.79 LMNA (0.45) ALDH1A1LMNA
SCHEMBL3267499 0.75 KDM6B (0.56) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL3099858 0.73 GAA (0.56) ALDH1A1LMNA
SCHEMBL9299031 0.72 ALDH1A1 (0.31) ALDH1A1LMNA
SCHEMBL11973891 0.72 ALDH1A1 (0.35) ALDH1A1LMNA
SCHEMBL8523298 0.72 DGAT1 (0.33) ALDH1A1LMNA
SCHEMBL1026048 0.71 KDM6B (0.54) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL3876828 0.69 KDM6B (0.33) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL8966176 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2255797-A2 COMPOSITE PREPARATION HanAll Biopharma Co., Ltd. (KR) 2010-12-01 EP claimed
US-20110038931-A1 COMPOSITE PREPARATION HANALL BIOPHARMA CO., LTD. (KR) 2011-02-17 US disclosed
EP-2255797-A2 COMPOSITE PREPARATION HanAll Biopharma Co., Ltd. (KR) 2010-12-01 EP disclosed