Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98444 | 0.83 | HDAC3 (0.36) | DGAT1SMN1; SMN2CYP2D6HDAC3HDAC1 | |
| SCHEMBL2648388 | 0.80 | DGAT1 (0.42) | DGAT1CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL28514999 | 0.79 | HDAC3 (0.33) | DGAT1SMN1; SMN2CYP2D6HDAC3HDAC1 | |
| SCHEMBL12136578 | 0.79 | LMNA (0.45) | ALDH1A1LMNACA12CA14MAPT | |
| SCHEMBL20237059 | 0.78 | ALDH1A1 (0.37) | DGAT1SMN1; SMN2CYP2D6HDAC3HDAC1 | |
| SCHEMBL23367225 | 0.76 | TDP1 (0.42) | SMN1; SMN2ALDH1A1CA2CA12CA14 | |
| SCHEMBL28068423 | 0.75 | CYP3A4 (0.38) | SMN1; SMN2CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL28068420 | 0.75 | CYP3A4 (0.38) | SMN1; SMN2CYP2D6HDAC3HDAC1HDAC2 | |
| SCHEMBL11592631 | 0.75 | ALDH1A1 (0.41) | DGAT1SMN1; SMN2CYP2D6HDAC3HDAC1 | |
| SCHEMBL241533 | 0.75 | DGAT1 (0.46) | DGAT1CYP2D6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375801-A | Micro-reaction system and method for continuously preparing (R) -3-hydroxy-5-hexenoic acid ester by using same | 复旦大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-111686809-A | Carbonyl reductase/isopropanol dehydrogenase co-immobilized catalyst and preparation method and application thereof | 复旦大学 | 2020-09-22 | — | — | CN | disclosed |
| EP-2546365-A1 | Genetic alterations in isocitrate dehydrogenase and other genes in malignant glioma | The Johns Hopkins University (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2319941-A2 | Method and apparatus for correlating levels of biomarker products with disease | GeneNews Inc. (CA) | 2011-05-11 | — | — | EP | disclosed |
| WO-1999021842-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | WO | disclosed |
| US-5863865-A | APPLYING PLANT GROWTH REGULATOR TO AN AREA WHERE SUCH CONTROL IS DESIRED | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |